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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRT
All Species:
11.21
Human Site:
S253
Identified Species:
27.41
UniProt:
O14522
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14522
NP_008981.4
1463
164346
S253
R
R
F
S
A
T
V
S
V
A
D
T
A
Q
R
Chimpanzee
Pan troglodytes
XP_512029
1532
172097
N292
R
R
F
I
A
S
F
N
V
V
N
T
T
K
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543002
1658
185145
S353
R
R
F
S
A
T
V
S
V
A
D
T
A
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99M80
1454
162994
S257
R
R
F
S
A
T
V
S
V
A
D
T
S
Q
R
Rat
Rattus norvegicus
Q64604
1898
211475
T473
N
T
D
A
G
L
L
T
T
V
G
S
L
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512422
1366
153344
V216
A
L
M
V
T
R
V
V
N
H
R
R
F
S
A
Chicken
Gallus gallus
Q6YI48
1434
161661
Q249
R
R
F
L
A
T
F
Q
L
D
E
V
S
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DK56
1444
162642
Q246
N
R
F
A
V
S
F
Q
L
E
D
V
Q
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16621
2029
229038
S479
N
S
E
L
T
T
V
S
E
L
T
P
H
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BMN8
2200
246601
E619
R
G
Q
G
E
F
T
E
P
M
I
S
K
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.5
N.A.
85.3
N.A.
97.7
26.3
N.A.
84.4
51.6
N.A.
52.1
N.A.
26.7
N.A.
23.9
N.A.
Protein Similarity:
100
76
N.A.
85.7
N.A.
98
42.4
N.A.
88.3
71
N.A.
69
N.A.
40.4
N.A.
39
N.A.
P-Site Identity:
100
46.6
N.A.
100
N.A.
93.3
0
N.A.
6.6
33.3
N.A.
20
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
26.6
N.A.
6.6
60
N.A.
46.6
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
50
0
0
0
0
30
0
0
20
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
40
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
10
10
10
10
0
0
0
0
% E
% Phe:
0
0
60
0
0
10
30
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
10
10
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
30
0
% K
% Leu:
0
10
0
20
0
10
10
0
20
10
0
0
10
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
30
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
20
% P
% Gln:
0
0
10
0
0
0
0
20
0
0
0
0
10
30
0
% Q
% Arg:
60
60
0
0
0
10
0
0
0
0
10
10
0
0
40
% R
% Ser:
0
10
0
30
0
20
0
40
0
0
0
20
20
10
0
% S
% Thr:
0
10
0
0
20
50
10
10
10
0
10
40
10
10
0
% T
% Val:
0
0
0
10
10
0
50
10
40
20
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _